Vasoactive mediators and hypotensive transfusion reactions
نویسندگان
چکیده
منابع مشابه
Immunomodulatory mediators in platelet transfusion reactions.
Our appreciation of the roles that platelets play in vascular biology is constantly expanding. One of the major roles of platelets is in initiating and accelerating immune responses. Platelet transfusion may be associated with adverse inflammatory outcomes manifested as fever, discomfort, tachycardia, and respiratory issues. This may in part be due to immune mediators either expressed by activa...
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OBJECTIVES To examine whether a liver transplant patient, who was not taking an angiotensin-converting enzyme inhibitor and developed two episodes of hypotension with systolic pressure in the 50s within minutes of starting an RBC transfusion, may have had a disturbance in the production and metabolism of bradykinin and des-Arg(9)-BK. METHODS All patient information was obtained by reviewing t...
متن کاملTransfusion reactions.
Blood components are indicated in a wide variety of disease states. Although most transfusion therapies are administered uneventfully, there are a number of potential adverse transfusion reactions, some of which can assume serious dimensions. These reactions could occur during or even days after a transfusion. A brief description of the adverse effects of transfusion therapy has been outlined i...
متن کاملAutologous blood transfusion and hypotensive anesthesia for rotational acetabular osteotomy.
We employed hypotensive anesthesia with prostaglandin E1 (PGE1) and transfused 400 ml of autologous whole blood on the first postoperative day to avoid homologous blood transfusion in 137 patients undergoing rotational acetabular osteotomy (RAO) and RAO combined with intertrochanteric valgus osteotomy. Four hundred ml of whole blood were donated 1 week before the surgery, and transfused on the ...
متن کاملFebrile nonhemolytic transfusion reactions.
A. FNHTRs are reported in 0.5%–5% of all transfusions. B. FNHTRs are the most common complication of platelet transfusion. 1. Incidence ranges from 1.7% to 31%. 2. Higher incidences are seen in patients who have received multiple prior transfusions. C. Incidence may decrease with increased use of prestorage leukocytereduced blood products. D. Higher incidence of blood transfusion reactions occu...
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ژورنال
عنوان ژورنال: Transfusion
سال: 2007
ISSN: 0041-1132,1537-2995
DOI: 10.1111/j.1537-2995.2007.01154.x